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Higher blood-lead in pregnant BD women: Study

Higher blood-lead in pregnant BD women: Study

Powdered turmeric, agrochemicals, lead-soldered cans possible sources
Dhaka, July 18 – Presence of higher blood lead level (BLL) has been found in pregnant women of rural areas in Bangladesh, said a recent icddr,b study done in collaboration with Stanford University, USA. A third of pregnant women surveyed were found having elevated BLL greater than 5 micrograms per deciliter (DL) while 6 percent of them had more than 10 micrograms per DL. One sample was found at 29.1 micrograms per DL, which is 6 times greater than the threshold noted by the Center for Disease Control and Prevention (CDC).
Findings published in Environmental Research analysed BLL among 430 pregnant women in some districts, said icddr,b on Monday.
The study identified multiple possible sources of lead exposure from the environment and food sources, said Professor Stephen P. Luby, senior author of the study and professor of medicine at Stanford University.
“Compared to women with low blood lead levels, women with the highest blood lead levels were more likely to be exposed to consuming food from lead-soldered metal food containers (cans), consuming food from agricultural fields where herbicide and pesticides have been used and consuming ground rice,” said Sarker Masud Parvez, co-author of the study and research investigator at icddr,b.
Since women with higher BLL were more likely to have been exposed to possible lead sources in the environment, the researchers examined soil, 382 agrochemical samples including herbicides and pesticides and 127 ground and unground rice samples.
Of the food and agrochemical samples analysed, seven out of 17 turmeric powder samples had the excess lead than the tolerable limit at 2.5 micrograms per gram, designated by Bangladesh Standards and Testing Institution (BSTI). One unpackaged and unbranded sample contained over 265 microgram/gram lead.
According to the Centre for Disease Control and Prevention (CDC), elevated BLL in pregnant women is a cause for public health concern. It is a threat for mothers and their developing fetus as well for the newborn as lead deposits in the mother’s body are released in blood and subsequently into breast milk. Lead exposure in pregnancy interferes with children’s brain development. In adults, lead exposure increases the risk of heart and brain diseases.
Since women with higher BLL were more likely to consume food from lead-soldered food cans, the researchers examined 28 cans which the women had used to store dry food such as puffed rice and turmeric.
“It is possible that food stored in these cans absorbs lead from the soldered seams, depending on the chemical composition of the food, especially liquid,” said Jenna E. Forsyth, a doctoral researcher at Stanford University and first author of the study.
However, the women reported storing only solid food such as puffed rice. Since these cans are old and rusty, it is possible that old and rusted oxidised particles flake off into the puffed rice and then inadvertently consumed, read the study.
Since there was an insignificant lead level in the soil, rice and agrochemical samples analysed, the study notes that currently banned agrochemicals (herbicide and pesticide) may have contributed to lead exposure in the past.
“Lead exposure over time results in lead deposit in the bones and it may be released in the blood during pregnancy,” mentioned Dr Rubhana Raqib, co-author of the study and senior scientist and head of immunobiology, nutrition and toxicology laboratory at icddr,b.
Therefore, it cannot be ruled out that exposure to lead for these women could have taken place over a decade prior to sample collection, the study noted. Some of the banned agrochemicals are often rebranded with other names and may be a source of occasional contamination which is yet to be proven.
However, the tangible evidence of lead in some turmeric samples issues a warrant to investigate this further to ascertain possible sources of lead contamination.
The study was supported by Stanford University’s Woods Institute, USAID, Stanford’s Emmett Interdisciplinary Program in Environment and Resources, Stanford’s Center for South Asia, and the Bill and Melinda Gates Foundation. – UNB